GLIOMA: 80% of primary malignant tumors
WHO I:
PILOCYTIC ASTROCYTOMA
WHO II:
DIFFUSE ASTROCITOMA
OLIGODENDROGLIOMA
OLIGO-ASTROCYTOMA
WHO III:
ANAPLASTIC ASTROCYTOMA
ANAPLASTIC OLIGODENDROGLIOMA
WHO IV:
GLIOBLASTOMA MULTIFORME
L
o
w
G
r
a
d
e
H
i
g
h
G
r
a
d
e
Natural history
Moving to biomolecular classification