Particle Therapy 2017

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Fx: b.i.d. (1.8 GyE x 2), 50 fxs, 5 wks

3 volumes: V1 (90 GyE), V2 (64.8 GyE),

V3 (50.4 GyE)

Tumor progression: 16/23 (1 in 90 GyE

vol.)

Toxicity: necrosis in all 23 pts

Fitzek, MGH-HCL, 1999

Tumor progression: 16/23 (1 in 90 GyE volume)

Open issue: Identification of target volume ?

Glioblastoma

Therapeutic Results - Protons