Particle Therapy 2017

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Microdosimetric Kinetic Model
(courtesy of N. Matsufuji)
Single lesion in any domain
leads to cell death
Hawkins, Rad. Res. (2003)
Kase et al., Rad. Res. (2006) 15
~10 μm ~1 μm
TDRA +MKM
z: spec. energy
y: lineal energy