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LATE EFFECTS: PROGNOSTICATORS

Radiotherapeutical management

Total dose

Fractionation

Target volume

Technology

Individual status:

Genetic predisposition (ex. Li Fraumeni)

Individual sensitivity

Patient’s age

Gender

Tumor expansion, hydrocephalus

Combined therapy

Chemotherapy (ex. cisplatin

ototoxicity)

Surgery (ex. Hypothalamic resection

appetite disorders, obesity)