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MEMORANDUM
Date:
June 22‐23, 2017
To:
AOAC INTERNATIONAL Official Methods Board
From:
Sidney Sudberg, Chair – Committee on Statistics / OMB Member
Subject:
Item Vb – Summary of Activities for the AOAC Committee on Statistics
1.
Progress updates
a.
Statistics for Microbiology methods validation,
1.
Testing/Validating of the new spreadsheets for both Qualitative &
Quantitative calculations actively moving forward
b.
Changes to Appendix J (after1.a.1. above complete)
1.
Quantitative methods need changes (performed during &/or after
validation)
1.
Candidate minus Reference
2.
New method of calculating the CI for the paired DPod
3.
Use of Z (n) vs. t (n‐1)
4.
Removal of reference to Welch/Satterthwaite t‐test?
5.
Chi‐Square Test Calculator
http://lcfltd.com/AOAC/aoac‐binary‐v2‐
5.xlsx
c.
Revising of Stat Committee’s Terms of Reference (TOR)
1.
Committee should have something to review
d.
Intermediate Precision (IP) Working Group:
1.
Appropriate applicability for use of IP: Completed
1.
SLV
2.
First Action
2.
Committee on Statistics to produce a separate appendix &/or Glossary, i.e.
remove statistical details from various appendices?
1.
Appendices J, K & others
e.
Appendix K Revision to begin:
1.
Terms, Definitions & its’ Measurement need to be defined
1.
Intermediate Precision
2.
LOD/LOQ
f.
Proficiency Testing Data for:
1.
Collaborative Studies: Chondroitin Collab Study
2.
Validation
3.
TDRM interaction & the use of qualified Reference Standards
g.
Incremental Collab Studies
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