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Liposomes, Exosomes, and Virosomes: From Modeling Complex
Membrane Processes to Medical Diagnostics and Drug Delivery
Tuesday Speaker Abstracts
30
Cotranslational Protein Folding
Gunnar Von Heijne
.
Stockholm University, Stockholm, Sweden
We have developed a technique based on the use of so-called translational arrest peptides to
measure forces acting on a nascent chain during cotranslational processes such as membrane
translocation and folding. In contrast to hard-core biophysical methods, the technique can be
used both in vitro and in vivo. Recent results on cotranslational folding of cytoplasmic and
membrane proteins will be presented.