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Supporting study #1
112 patients with (chemo)radiation for a N2 headneck tumor
FDG-PET/CT scan 3 months after CRT
Only FDG-positive necks received node dissection
All others wait-and-see
Average follow-up 2,5 years
Results
50 patients with residual nodes on CT
9 positive on PET:
PPV = 22%
41 negative on PET:
NPV =
100%
Results of a prospective study of positron emission tomography-directed management of residual nodal abnormalities in node-positive
head and neck cancer after definitive radiotherapy with or without systemic therapy.
Porceddu SV et al., Head Neck 2011. (Aus)