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Assessing Therapy: Cervical Cancer
n=60
IB
2
-IVB/recurrent
Tumor
regression rate
(fast
vs. slow) at mid-RT (45–50
Gy) best outcome
prediction for local control
(84% vs. 22%,
p
< 0.0001) &
disease-free survival
(63%
vs. 20%,
p
= 0.0005)
N=80
IB2 through IVA
Combination of
pre RT
tumour volume & MRI
regression ratio 4-5 weeks
post CRT
best predictor of
local control: 89%
sensitivity, 87% specificity,
88% accuracy for LR
Mayr et al. Int J Radiat Oncol Biol
Phys 2002;52(1):14-22
Wang et al. Cancer 2010;116(21)
5093-101.