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Assessing Therapy: Cervical Cancer

n=60

IB

2

-IVB/recurrent

Tumor

regression rate

(fast

vs. slow) at mid-RT (45–50

Gy) best outcome

prediction for local control

(84% vs. 22%,

p

< 0.0001) &

disease-free survival

(63%

vs. 20%,

p

= 0.0005)

N=80

IB2 through IVA

Combination of

pre RT

tumour volume & MRI

regression ratio 4-5 weeks

post CRT

best predictor of

local control: 89%

sensitivity, 87% specificity,

88% accuracy for LR

Mayr et al. Int J Radiat Oncol Biol

Phys 2002;52(1):14-22

Wang et al. Cancer 2010;116(21)

5093-101.