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Slide 24
FDG-PET based RT planning in NSCLC:
first clinical data
44 pat. NSCLC I-III, 10/44 mediastinal downstaging by PET
Dose escalation to 64,8 Gy/1,8 Gy b.i.d.
GTV = tumor + FDG-PET positive LN-stations
18 local recurrences (41 %)
after median follow up of 16 months
1 isolated out field recurrence
at LN pre treatment N0 in CT and PET
De Ruysscher IJROBP 2005 62; 988-994