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Standard of care: general agreement
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Exclusive Radiochemotherapy
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MMC/5FU (or capecitabine)
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(CDDP/5FU)
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No benefit for neoadjuvant chemotherapy
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No benefit for maintenance
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IMRT
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Can reduce acute toxicity
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High gradient dose between tumor
and normal tissue
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Needs accurate delineation and control
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No Gap
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Good outcomes:
5-year survival=70 %