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Source-to-background algorithms
signal intensity
position
I
bg
I
source
T = C·I
source
+ I
bg
•
Constant C determined from phantom measurements
•
Works very well for quasi-spherical lesions
•
Value of C depending of different factors:
•
Lesion size and shape
•
Scanner type and calibration
•
Reconstruction protocol
•
Image analysis software
Schaefer et al, EJNMMI
2008; 35(11): 1989-99.
PET image
Line profile