657 / 1241
Nodal staging (n=311)
Axilla
• Sens 82 % NPV 53 %
• Spec 92 %
PPV 98 %
58 new node areas in 56 pts
• 32 periclavicular area
• 26 internal mammary chain
Conclusions
• FDG PET/CT cannot replace SLNB when negative
• FDG positive nodes are highly predictive for N+, no SN
• FDG PET/CT frequently upstages to N2 or N3
Pre-chemotherapy 18F-FDG PET/CT upstages nodal stage in stage II-III
breast cancer patients treated with neoadjuvant chemotherapy. Koolen BB
et al. Breast Cancer Res Treat. 2013 Sep;141(2):249-54.
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