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Biological concept
• Start of treatment
• Damage to tumor cells
Days
• Loss of cellular functions
PET
• Cell death (apoptosis)
• Leakage of signal molecules
• Activation of immune system
• Increase of mass and perfusion
Weeks
• Tissue fragments and fagocytosis
dwiMR
• Formation of scar tissue
• Reduction in perfusion
ceMR
• Shrinkage of tumor mass
Months
CT
• End result
12