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Chapter 2

34

MATERIAL AND METHODS

The local Institutional Review Board of the Erasmus MC in Rotterdam waived the need for

consent. The participation in this survey was voluntary, and no patient identifiers were

collected.

The cross-sectional

survey

was conducted between July and November 2013. The online

questionnaire was composed of 59 questions regarding local nutritional protocols and

strategies, and provided in English, French, Spanish and Chinese. The second part, the

point

prevalence

, conducted between May and September 2014, involved data collection on

nutritional practices and intake for the preceding 24 hours. In a subgroup of centers that

agreed to participate in this portion of the study, respondents were asked to include data for

all patients present in their PICU; no selection criteria were applied. Both questionnaires are

available as an

online supplement

(Supplementary Digital Content:

http://links.lww.com/PCC/

A204).

Testing of clarity, relevance, and clinical sensibility of the English questionnaire was performed

by independent clinicians in three centers (Sophia Children’s Hospital-Erasmus MC, Rotterdam,

the Netherlands; University Hospital of Leuven, Belgium; and the Boston Children’s Hospital,

Boston, MA). Data from this test were not included in the final analysis and survey results.

Afterward, the questions were translated to French, Spanish, and Chinese by native speakers.

An invitation to the

survey

was electronically distributed to members of the World Federation

of Pediatric Intensive and Critical Care Societies (WFPICCS) by their mailing list and to specific

members of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC) and

Society of Critical Care Medicine involved in nutritional management and through the

newsletter of both the ESPNIC andWFPICCS and the WFPICCS homepage and LinkedIn group.

A reminder was sent 2 months after the first invitation. Due to incomplete data registration,

the exact number of PICUs represented by the WFPICCS database is unknown. Respondents

who provided their contact information in the

survey,

were approached to participate in the

point prevalence

.

If more than one questionnaire was returned from a single PICU, the answers were weighted

by the inverse of the number of completed questionnaires per center, in order to process

conflicting statements within a single institution without disrupting the weight of the answers

per PICU. Countries were classified by income according to The World Bank income groups

16

.

Individual questions were stratified by continent, income of country, number of PICU beds,

admissions per year, and percentage of ventilated patients.

Statistical analysis was performed using IBM SPSS statistics 21 for Windows (IBM, Chicago,

IL). Descriptive statistics were used to compare differences in respondent characteristics

and survey responses. Nutritional data obtained in the

point prevalence

were compared to