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z = 4

t > 1.28

2.8

2.7

2.9

3

3.2

3.6

4

3.2

3.6

4

anterior

posterior

t -value

Reward

Reward x

Task switch

Reward x Task switch x

Response switch

A

B

3

5

2

4

3.5

2.5

1.5

2

4

6

5

3

t -value

peak: x = 6, y = 16, z = 2

peak: x = -6, y = 6, z = -6 peak: x = -28, y = -8, z = 8

z = 8

z = 2

t > 3.14*

t > 2.61

y = 3

y = -8

t > 3.14*

y = 16

151

Controlling dorsolateral striatal function via anterior frontal cortex stimulation

Figure 7.5

Effect of aPFC stimulation (versus baseline) for Reward (red), the interaction

between Reward and Task switching (green), and between Reward, Task switching and

Response switching (blue)

A:

To visualize the gradients in the striatum, the whole-brain maps for these three contrasts are shown

in one image at a low threshold (t = 1.28, p < 0.1). We applied a filter over the image to visualize the

anterior-posterior and medial-lateral gradient in the striatum.

B:

Whole-brain maps at PUNC < 0.001, t > 3.14 (left and right) and at PUNC < 0.005, t > 2.61 (middle)

for Reward (left), Reward x Task switching (middle) and Reward x Task switching x Response switching

(right).

Asterisks (*) and black dashed circles indicate a significant effect of Reward (left) and the Reward x Task

switching x Response switching (right) (PFWE < 0.05 within the search volume, i.e. the caudate nucleus

or putamen, respectively) and red and blue dashed lines indicate the z-coordinates for the peaks of these

respective effects to visualize the ventral to dorsal gradient.