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Table of contents

Chapter 1

Striatal dopamine and motivated cognitive control

7

Chapter 2

General introduction and thesis outline

27

Chapter 3

Human cognitive flexibility depends on dopamine D2 receptor signalling 47

Supplementary material

65

Chapter 4

Reward modulation of cognitive function in adult ADHD

74

Chapter 5

Reduced effects of reward motivation on flexible cognitive control across

the life span

99

Supplementary material

114

Chapter 6

The nucleus accumbens core mediates the beneficial effect of reward on

flexible behavioural control: evidence from cross-species translation

117

Chapter 7

Controlling dorsolateral striatal function via anterior frontal cortex

stimulation

137

Chapter 8

General discussion

161

Appendix

References

182

Nederlandse samenvatting

201

Dankwoord |Acknowledgements

208

Bibliography

212

List of publications

213

Donders Graduate School Series

214