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Chapter 4
Table 4.3
Mood and neuropsychological assessment
ADHD OFF
ADHD ON
HC
Univariate or repeated measures GLM
(unless noted otherwise)
9R
carriers
10R/10R
9R
carriers
10R/10R
9R
carriers
10R/10R
ADHD OFF
vs. HC
ADHD ON
vs. HC
ADHD ON
vs. ADHD
OFF
DIAGNOSIS
x
DAT1
MPH x
DAT1
Bond & Lader mood scales
F(1,44)
F(1,45)
F(1,20)
F(1,44)
F(1,20)
Contentedness
67.42
(4.58)
66.91
(7.15)
76.86
(3.84)
76.82
(4.63)
84.69
(3.50)
77.05
(2.82)
F = 8.78;
p
< .005
MWU =336.5;
p
> .05
Wc= 50;
p
= .013
F < 1
F < 1
Alertness
49.36
(4.19)
57.15
(5.90)
71.79
(3.99)
69.38
(4.66)
78.52
(5.15)
69.74
(2.62)
F = 22.74;
p
< .001
F =1.42;
p
> .05
F =22.73;
p
< .001
F = 3.58;
p
> .05
F = 1.96;
p
> .05
Calmness
59.73
(4.44)
49.46
(7.75)
58.91
(6.07)
62.00
(6.91)
83.40
(4.56)
74.72
(3.52)
F = 22.46;
p
< .001
F = 13.26;
p
< .001
F = 1.14;
p
> .05
F < 1
F = 1.485,
p
> .05
Neuropsychological assessment
Motor speed
(RT, sec)
54.09
(2.60)
54.27
(3.44)
55.18
(3.32)
53.36
(2.34)
69.67
(8.51)
64.31
(6.05)
MWU = 355.5;
p
> .05
MWU = 356;
p
> .05
F<1
F < 1
MWU =
230;
p
> .05
Vigilance
(RT)
219.64
(13.65)
204.46
(10.39)
222.00
(10.36)
199.73
(9.79)
204.67
(8.41)
210.09
(9.23)
F < 1
MWU =289;
p
> .05
Wc = 122;
p
> .05
F < 1
F < 1
Vigilance
(misses)
5.09
(1.42)
5.00
(1.05)
2.46
(0.64)
3.82
(1.12)
2.72
(1.12)
2.78
(0.61)
MWU = 177.5;
p
= .024
MWU = 256;
p
> .05
Wc = 150;
p
= .026
KW (3) =
5.418;
p
> .05
MWU =
311;
p
> .05
Verbal fluency
(no. of words)
37.55
(3.82)
42.27
(3.21)
38.18
(3.48)
43.36
(3.48)
46.89
(3.66)
42.16
(2.11)
F = 1.42;
p
> .05
F<1
F < 1
F = 1.51;
p
> .05
F < 1
KW = Kruskal-Wallis test; MWU = Mann Whitney U test;
Wc = Wilcoxon paired rank test; MPH = methylphenidate; 10R/10R = 10R homozygotes