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Involved Site Radiotherapy

(ISRT)

o

ISRT accomomodates cases in which optimal prechemotherapy imaging is

not available to the radiation oncologist

o

In these situations, it is not possible to reduce the CTV to the same extent

as with INRT, because the prechemotherapy GTV information may not be

optimal

o

In ISRT, clinical judgment in conjunction with the best available imaging

is used to contour a larger CTV that will be accommodate the uncertainties

in defining the prechemotherapy GTV