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IMRT minimizes the amount of normal tissue getting high doses

But IMRT does result in larger volumes of normal tissue getting lower

doses (

more fields and more leakage

)

Which is preferable in terms of second cancers?

Small volumes of normal tissue getting high doses (3D-CRT)

Larger volumes of normal tissue getting low doses (IMRT)

Second Cancers: IMRT vs. 3D-CRT