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What Drives Radiation Sensitivity in Lymphoma?
The old radiobiology view of
RT sensitivity in lymphoma
Lymphoma = Apoptosis = Radiosensitive
RT sensitivity in lymphoma,
in the molecular age…
Lymphoma gene expression profiles may predict
differences in radiosensitivity
Figure from:
Radiobiology for the Radiologist
By Eric J. Hall, Amato J. Giaccia
Wide spectrum of response to RT in lymphoma (4-40 Gy):
Dramatic variations in radiosensitivity can be explained by
molecular differences in the tumor