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Toxicity

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Immediate toxicity consists of mild to moderate cutaneous or

conjunctival reactions

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Long-term complications are observed in up to 50% of patients

o

The complications are relatively minor and include cataract

formation (30-50%) and mild xerophthalmia (20-40%)

o

RT doses above 36 Gy may result in deleterious ophthalmologic

toxicity such as ischemic retinopathy, optic atrophy, corneal

ulceration, neovascular glaucoma, associated with significant vision

loss