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Recent Trends-increasing the role of RT in salvage of HL

Radiation alone - obsolete

Combined modality programs -

decreasing

Radiation fields – markedly reduced

(ISRT by ILROG)

Radiation dose – from 40 Gy to 20-30 Gy

Chemotherapy alone -

increasing

Advanced-stage

Early-stage

(>50% of U.S. patients, most women)

New effective agents integrated in front line therapy

Brentuximab Vedotin

Check point inhibitors

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