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Integrating Radiotherapy -

Preferred

Pre-transplantation RT

as part of the response-inducing regimen

Induce maximal tumor reduction when it is most critical

Differential dose to relapse/bulky site vs. all nodal sites (TLI)

Completed within 10 days (36 Gy b.i.d program)

Safe and rarely toxic

Non-myelosuppressive or leukomogenic