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Non-Adaptive Regimens:

How RT was added or tested?

MOPP/ABV hybrid-

EORTC

(obsolete)

Original volume IFRT 24 Gy (

vs

none

); 30 Gy for PR- response by CT

ABVD (non-adaptive) 6-8 cycles

IFRT 36 Gy often to original, or CR?/PR (by CT)- to bulk or all sites

Stanford V

IFRT 36 Gy to originally >5 cm disease sites or spleen

Escalated BEACOPP (variety of schedules)

IFRT 30-40 Gy to bulky sites/residual sites (HD - landmark GHSG study)