Non-Adaptive Regimens:
How RT was added or tested?
•
MOPP/ABV hybrid-
EORTC
(obsolete)
–
Original volume IFRT 24 Gy (
vs
none
); 30 Gy for PR- response by CT
•
ABVD (non-adaptive) 6-8 cycles
•
IFRT 36 Gy often to original, or CR?/PR (by CT)- to bulk or all sites
•
Stanford V
–
IFRT 36 Gy to originally >5 cm disease sites or spleen
•
Escalated BEACOPP (variety of schedules)
–
IFRT 30-40 Gy to bulky sites/residual sites (HD - landmark GHSG study)




