1556 / 1835
RT in PCNSL – Take home
•
WBRT an effective tool in many stages of treatment
•
Best use of RET is as low dose (24 Gy) after CR to MTX
•
Full dose RT after MTX is toxic in age >60 years
•
Chemotherapy alone in “full” MTX doses or with ASCT
transplant is also toxic, but is often considered
•
Patients respond (yet, temporarily) to salvage with RT
alone or with chemotherapy