1739 / 1835
Diagnosis:
•
A CT-guided percutaneous biopsy: DLBCL.
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sheets of malignant large lymphocytes which were CD79a+, CD20+ confirming B-cell
origin.
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Further immunohistochemistry confirmed activated B-cell subtype of DLBCL, which is
MUM1+, BCL2+, BCL6+, p53+, CD30+/-, CD10+/-
–
proliferation fraction (Ki67) > 90%.
–
In situ hybridization showed no MYC, IgH, BCL2, or BCL6 rearrangements.