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How would you treat this patient

A. 6 x R-CHOP

B. 6 x R-Bendamustine

C. 3 x R-CHOP + ISRT

40 Gy

D. 3 x R-CHOP + ISRT

30 Gy

6 x R-CHOP

6 x R-Bendamustine

3 x R-CHOP + ISRT 40 Gy

3 x R-CHOP + ISRT 30 Gy

25% 25% 25% 25%