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Results with R-CHOP in DLBCL

5-year survival according to aaIPI & age*

aaIPI score = 0:

>85%

Young, aaIPI score = 1:

>80%

Young, aaIPI score >1:

60%

Elderly, aaIPI score >0:

50%

Very old:

30%

For 30-40% of patients, R-CHOP is not satisfactory

*

Poor performance status (ECOG 2-4); Elevated LDH; Stage III or IV