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Results from the trials
Early stage disease
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Chemotherapy improves the cure rate over radiation alone (EORTC-H7)
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Sub-optimal chemotherapy (EBVP) needs RT for best results (EORTC-H9)
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Reducing size of the radiation field is safe
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Reducing the radiation dose is possible for good prognosis disease, or after
adequate chemotherapy
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Omitting radiotherapy altogether may be possible for some patients: can we
predict who they are?