RT can induce immunogenic tumour cell death (ICD)
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Understanding more about effect of RT dose and fractionation on DAMP
release and ICD will be important in making progress
RT a potentially important component to improve systemic anti-tumour
immunity
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Overcoming extrinsic tumor micro-environmental immunosuppressive factors
critical to exploiting systemic anti-tumour immune responses to RT
The efficacy of RT can be greatly enhanced in combination with
immunoregulatory agents and holds great promise to improve outcome
for a range of cancers
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Well designed clinical trials required with high quality translational science
including immunological biomarkers of response




