922 / 1835
Incidence
• 5%
of all HL
• 1.5 /
1m
population/ y
• Recently recognized category:
– 1944:
Jackson & Parker
:
granuloma
variant of HL
– 1994:
REAL
classification (CD20+ LP, L&H/ popcorn cells)
– 2001:
WHO
(separated from cHL as NLP)
• No prospective studies:
– Re-analysis
of previous studies
– Institutional
/
registry
based retrospective studies