1075 / 1816
Stratification
▪
Axillary nodes removed (<10, >10)
▪
Positive axillary nodes (0, 1-3, >3)
▪
Chemotherapy (anthracycline, other, none)
▪
Endocrine therapy (yes, no)
Study Design
WBI
WBI + RNI
Node Positive or
High Risk
Node Negative
Post-BCS
R
A
N
D
O
M
I
Z
E
Time period: 2000-2007
Primary endpoint OS
Sec endpoints DFS, locoreg
DFS, distant DFS