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Different endpoints for pCR after NAC
•Pathological complete response (pCR)
• pCR in breast and lymph nodes
• pCR in breast
• ypT0 ypN0
•
Absence of invasive cancer in the breast and axillary nodes
•
Absence of DCIS
• ypT0/is ypN0
•
Absence of invasive cancer in the breast and axillary nodes
•
DCIS allowed
• ypT0/Tis
•
Absence of invasive cancer in the breast
and DCIS allowed
•
Regardless of nodal involvement