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Restaging the axilla

Invasive re-staging:

SN after PST – with confirmatory ALND

SENTINA trial

1

; ACOSOG Z1071

2

and FNAC trial

3

Prospective cohort study

4

(no ALND if ≥ 3 SN negative)

Removal of clipped pathological node – with confirmatory ALND

MARI

5

(Marking of the Axilla with Radioactive Iodine)

Clipped node i.c.w. SN

2,6

RISAS study: recruiting

1

Kuehn et al 2013;

2

Boughey et al 2013, 2016, 2017

3

Boileau

et al 2015;

4

Mamtani et al 2016;

5

Donker et al 2015;

6

Caudle

et al 2016.