1570 / 1816
RT after Flap
reconstruction
Pooled rate (95% CI)
RT before Flap
reconstruction
Pooled rate (95% CI)
Complication
14% (0-0.38)
10% (0.04-0.77)
Wound healing
13% (0.07-0.2)
10% (0.06-0.14)
Fat necrosis
6% (0.03-0.1)
4% (0.02-0.06)
Infection
1% (0.01-0.04)
2% (0.01-0.04)
Hematoma
4% (0-0.12)
4% (0.02-0.05)
Seroma
27% (0.12-0.45)
-
Flap fibrosis
4% (0-0.04)
1% (0-0.02)
Flap loss
-
6% (0.03-0.11)
Partial flap necrosis
-
4%(0.03-0.06)
Vascular thrombosis
(reoperation)
Kelley, Ann Surg Onc 2014
Similar rates of complications and success
for pre- and post-reconstruction RT
Immediate autologous reconstruction
should be considered as a valuable
option even when PMRT is indicated (up to
4%
flap loss)
Timing of RT and reconstruction
FLAP