ESTRO Multidisciplinary Management of Breast Cancer 2017

Phase III: Boost for DCIS: BONBIS Trial (France)

Randomization

WBRT (50Gy)

WBRT + Boost (16

Gy)

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N=1 950 DCIS

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Closed

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Designed to detect a difference of 7% vs. 4%-

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Planned analysis based on number of IBTRs