475 / 1816
Ductal carcinoma in situ
▪
DCIS per se does not increase breast cancer
mortality
▪
Tumour cells are restricted to ductulo-lobular
units not invading beyond the basement
membrane
▪
Non-obligate precursor for invasive disease
▪
Risk for progression 14 – 53 %
▪
50 % of recurrences are invasive
▪
Due to screening activities lesions are identified
at an earlier stage
▪
Improved pathologic work up – improves risk
assessment