600 / 1816
Actual key-questions:
What is the probability that tumorcells are left in situ?
•
Is this dependent on margin width ?
YES !
What is the estimated amount of tumorcells left in situ ?
•
Is this dependent on margin width ?
NO ! Other factors
more important, like age, grade and subtype:
•
Chen et al 2014: simulation study &
•
Mihalcik et al 2017, analysis of LR, re-excision and
residual disease, N = 1073
Why is there no relation between LR and margin width > 0 cm ?