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What happens if you accept focally involved margins ?
•
Dutch Cancer Registry, 2003-2006: N = 22.450
•
Boost only given if Risk Factors like G3, LVI, Age < 50 yr, or
Focally
involved margins
•
5 yr IBTR :
2.38%
(2.18-2.60%)
•
NKI/AVL, 1980-2008 : N = 8485
•
5 yr IBTR:
2%
( if < 40 yr: 4%)
•
10 yr IBTR:
5%
(if < 40 yr: 9%)
Van der Heiden et al, Ann Oncol 2015
Results in the Netherlands:
Bosma et al, Br C Res Tr 2016