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Take home message for APBI/Boost:

Image-guidance for partial breast irradiation

Clips can be representative for

the location of the tumor bed

the location of the whole breast

Registering on clips is time-efficient and can allow for

margin reduction of the tumour bed PTV

kV-CBCT, MV-CBCT, 2D kV are equivalent in terms of

accuracy if registering on clips

2D MV as well, if clips are visible

Penninkhof Radiother Oncol 2009