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How to manage women with a positive SLNB?

Completion clearance or radiotherapy

Regional recurrence rates are very

low, (2%) and depend on tumour

biology, patient age and tumour size

Seminal trial: ACOSOG Z0011 trial.

800+ women with +ve SLN

randomised to completion clearance

or lower axillary RT as part of

standard breast RT fields.

At 6 years median FU, regional rates of

recurrence were 0.5% versus 0.9% and

not significantly different