How to manage women with a positive SLNB?
•
Completion clearance or radiotherapy
•
Regional recurrence rates are very
low, (2%) and depend on tumour
biology, patient age and tumour size
•
Seminal trial: ACOSOG Z0011 trial.
•
800+ women with +ve SLN
randomised to completion clearance
or lower axillary RT as part of
standard breast RT fields.
•
At 6 years median FU, regional rates of
recurrence were 0.5% versus 0.9% and
not significantly different