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Radiotherapy after Mastectomy and Axillary Dissection

Conclusions 1

In these trials:

for pN0 women,

RT gave no significant benefit

for pN4+women,

RT gave significant benefit

Absolute reductions

10-year recurrence: 8.8% (75.1% vs. 66.3%)

20-year breast cancer mortality: 9.3% (80.0% vs. 70.7%)

Proportional reductions

Recurrence: 21% (

SE

6)

Breast cancer mortality: 13% (

SE

8)