88 / 1816
Conclusions for RT after BCS
•
Radiotherapy can reduce risks of recurrence and
of death from breast cancer
•
In these trials:
–
Big absolute benefit in recurrence and breast cancer
mortality for pN+ and high-risk pN0
–
Moderate absolute benefit in recurrence and possible
small benefit in mortality benefit for other pN0 women
–
No significant departure from “One-in-four” rule
24
Lancet 2011