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Case for homework – case 3

53 yr, lump cranially in left breast, slightly red skin and slight edema

Imaging: 8.2 x 5.7 x 2.8 cm and couple of pathological nodes

Biopsy: IDC gr 1, ER neg, Her2.neu pos

cT3/4 N1 M0 breast cancer left-sided

Treatment:

Primary systemic treatment with immunotherapy --. Clinically near

CR

MRM left; right preventive mastectomy: ypT0N0 (6/22 nodes with

signs of treatment response)

Locoregional RT, including 4

th

ICR 40 Gy/15 fx SKAGEN Trial 1

Adj. immunotherapy