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Medulloblastoma with extensive nodularity (MBEN)
- Overlaps with desmoplastic MB (10-15% of young children)
- Pronounced nodularity (macroscopic)
- Greatly expanded «pale islands» with more advanced neuronal
differentiation (neurocytes): previously called “cerebellar
neuroblastoma”
MBEN
- Infants (<3 years)
- Strong association with Gorlin
syndrome
- Better prognosis than other
subtypes (lower frequency of
mts, more sensitive to CT and
RT)