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Gandola L. et al, JCO, 27, 2009
Milan HART Study
- 1998-2007
- 33 pts (M1 9, M2 6, M3 17, M4 1)
- HART: CSI (39 Gy; 1.3 Gy/fraction bid)
posterior fossa boost up to 60 Gy (1.5 Gy/fraction bid)
- 7 pts aged < 10 yrs who achieved CT after chemo received a
lower dose to the neuraxis (31.2 Gy)
- Median 82 months follow-up
- 5 yr EFS 70%
- 5 yr PFS 72%
- 5 yr OS 73%