1464-1465 / 2437
•
Nodular desmoplastic medulloblastoma and
medulloblastoma with extensive nodularity (ND/MBEN)
have been associated with a more favorable outcome in
younger children
•
Can be cured without using radiation or consolidation
with high dose chemotherapy strategy
•
Different toxicity /efficacy profile of regimens used
Fertility (CPM, Thiotepa); Ototoxicity (CDDP)
Neurocognitive Methotrexate (Intrathecal MTX)
Lucie Lafay-Cousin – ASCO Meeting Chicago June 03
rd
2017
Background/Rational