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As of the data cutoff, median duration of response and median PFS have not been met

DURATION OF RESPONSE (INDEPENDENT REVIEW)

CR

b

PR

b

* Censored when discontinued study and patient in response at that time.

Response ongoing as of the data cutoff date (April 1, 2016).

a

Patient initially assessed as CR and recategorized as SD.

b

Response categorization based on best overall response.

*

113

*

a