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PAge54

11/20/2017 |

Author

Division

a

Olaf Witt

SIOP LGG 201X

age: 0 -20.99 years

histologically verified LGG

collection of

fresh frozen tumor tissue

for biomarker

determination

mandatory

.

Exception: single cases of stereotactic biopsy in which larger biopsy would

impose unacceptable risk to patient

Indication to start chemotherapy: progressive disease

on MRI, neurological function, visual function,

all infants

< 1 year

NO default first line radiation therapy

Inclusion Criteria