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Page Background

• Heterogeneous cohorts with respect to standard treatment

and timing of valganciclovir

• Valganciclovir was given only “

when there was no

evidence of progression

Selection of patients with valganciclovir exposure of 6

months after surgery or after 6 months of standard

treatment

Enrichment for favorable outcome

Creation of a new long-term benefitting sub-group of

patients

• No documentation of factors associated with longer

survival, e.g. extent of resection, IDH, MGMT etc.

Valganciclovir-treated patients

vs.

contemporary controls